Equal Incorporation of Both Parental Bacteriophage T7 Deoxyribonucleic Acid Strands into Intracellular Concatemeric Deoxyribonucleic Acid

Equal incorporation of both parental bacteriophage T7 deoxyribonucleic acid strands into intracellular concatemeric deoxyribonucleic acid.

After infection of Escherichia coli B with radiolabeled T7 bacteriophage, the parental deoxyribonucleic acid label was found in both polynucleotide chains of the intracellular T7 concatemer.

Enzymatic Synthesis of Deoxyribonucleic Acid. Iii. the Incorporation of Pyrimidine and Purine Analogues into Deoxyribonucleic Acid.

Deoxyribonucleic acid repair in bacteriophage.

Intracellular inactivation of bacteriophage T4 early deoxyribonucleic acid.

As previously shown, a small amount of polynucleotide material is added to parental T4 deoxyribonucleic acid (DNA) molecules within the first 5 min of infection. I have asked whether this process is essential for phage replication. Two approaches-one involving decay of (32)P incorporated into this "early DNA" and the other involving photoinactivation of bromodeoxyuridine-containing early DNA-in...

Thymidine incorporation into deoxyribonucleic acid by isolated rat liver mitochondria.

Isolated rat liver mitochondria can incorporate tritiated thymidine into DNA. The addition of deoxyribonucleotides and ATP are necessary. The process of incorporation was found to be inhibited to the extent of 92% by actinomycin D and only 14% by pancreatic deoxyribonuclease. The identification of the labeled product as mitochondrial DNA is supported by its insolubility in acid, resistance to a...